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|Age||Early 30s (Deceased)|
|Manga debut||Chapter 6|
|Anime debut||Episode 2|
Rei Takashima had short, cheek length, light-brown hair held in the style of a bob. She also had brown eyes. She wore red lipstick, a lab coat, glasses and a tight-fitting short black dress and had a mole under the left side of her mouth.
At first, Rei Takashima appears to be a level-headed and typical doctor, even showing remote signs of care for her patients. However, she receives immense pleasure from removing body parts and organs of fully-conscious Deadmen when they lose a Carnival Corpse similar to that of Minatsuki Takami and also becomes enraged when she doesn't get to remove a non-regenerative organ. Like most, if not all, staff at Deadman Wonderland, she is very sadistic.
Takashima is first introduced after Tamaki collapses a tower on Ganta. Ganta goes to her office, where she fixes him up and tells him about the candy. She appears a second time when she analyzes Senji's X-rays.
However, when Senji loses his battle against Ganta Igarashi, she more than happily removes his right eye and gains pleasure doing so, therefore exposing her sadistic side.
Later on, when Minatsuki faced her penalty of losing an organ at random, she only had to lose some of her hair as it had been rigged by the members of Scar Chain; this caused Takashima to become furious.
After the Deadmen defeated the Forgeries, she broke down crying and doubts that they could defeat Wretched Egg. However, Tamaki strangles her for doubting his goal to defeat Wretched Egg.
Near the end of the Deadman Wonderland revolt arc, she is seen busy in her laboratorium and eventually killed by an unknown being (most likely the Wretched Egg).
In an extra short-story in Chapter 12, incidentally tilted 'Perfect Man', Rei is shown treating an anatomical mannequin named "Tsutomu" as a lover with actions such as complaining to him about not being able to remove an organ or two from Minatsuki and that there's nothing wrong with her wanting to do so. She also accuses the mannequin of being a flirt because she can see right through him.
- In the anime's ending sequence she is implied to having worked in the same hospital as Karako once did.